Burn is a systemic injury and not just a skin injury. Burn care has developed over the years with the result of increasing in survival rate. The pathophysiology of burns is complex. An important part of the pathophysiology is fluid extravasation which can lead to shock. Inhalation injury can cause airway compromise. The management of burns start at the time of injury. Knowledge of the basic pathophysiology and the initial management of burns is essential for all the doctors, nurses and paramedical staff who may be the first attendant of the burn victims. In order to deliver a high standard care and to reduce the mortality of these patients, protocols and guidelines should be followed strictly.